Enhanced Sensitivity of Absorption Spectroscopy Glucose Detection by Machine Learning
DOI:
https://doi.org/10.4302/plp.v17i1.1319Abstract
In this study, UV-VIS spectroscopy was used as a tool for detecting low glucose concentrations in urine. Measurements were performed on artificial urine samples and solutions with 0.1% and 0.2% glucose, covering both normal and pathological thresholds. Among the evaluated models, Random Forest reached 0.887 for the 0.1% glucose sample, while Logistic Regression achieved 0.7796 for the 0.2% glucose sample, demonstrating high effectiveness in distinguishing glucose levels. The results confirm that the integration of UV-VIS spectroscopy and machine learning has the potential to serve as a fast and non-invasive screening tool for the early detection of metabolic disorders.
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References
- S. L. Cowart and M. E. Stachura, Clinical Methods: The History, Physical, and Laboratory Examinations, 3rd edition, chapter 139, 1990. DirectLink
- P. Sokołowski, P. Wityk, K. Cierpiak, M. Babińska, W. Graczyk, B. Krawczyk, M. Markuszewski and M. Szczerska, "Optical method supported by machine learning for urinary tract infections discrimination and bladder cancer detection", Optical Sensing and Detection VIII, Proc. SPIE, 12999, 129992B (2024). CrossRef
- T.-T. Wang, K. Guo, X.-M .Hu, J. Liang, X.-D. Li, Z.-F. Zhang and J. Xie, "Label-Free Colorimetric Detection of Urine Glucose Based on Color Fading Using Smartphone Ambient-Light Sensor", Chemosensors, 8(1) (2020). CrossRef
- P. Sokołowski, K. Cierpiak, M. Szczerska, M. Wróbel, A. Łuczkiewicz, S. Fudala-Księżek and P. Wityk, "Optical method supported by machine learning for dynamics of C-reactive protein concentrations changes detection in biological matrix samples", J. Biophoton., e202300523 (2024). CrossRef
- M. Jędrzejewska-Szczerska, M. Gnyba, M. Sobaszek and E. Krystian, "Spectroscopic wireless sensor of hematocrit level", Sensors and Actuators A: Physical, 202, 8 (2013). CrossRef
- P. Wityk, P. Sokołowski, M. Szczerska, K. Cierpiak, B. Krawczyk and M. J. Markuszewski, " P. Wityk, P. Sokołowksi, M. Szczerska, K. Cierpiak, B. Krawczyk and M. J. Markuszewski, Journal of Biophotonics,16(9), e202300095 (2013).", J. Biophoton.,16(9), e202300095 (2013). CrossRef
- R.T.Yunardi, R. Apsari and M. Yasin, "Comparison of Machine Learning Algorithm For Urine Glucose Level Classification Using Side-Polished Fiber Sensor ", J.Electronic.Electromed.Eng.Med.Inform, 2(2), 33 (2020). CrossRef
- A. Althnian, D. AlSaeed, H. Al-Baity, A. Samha, A.B. Dris, N. Alzakari, A. Abou Elwafa and H. Kurdi, "Impact of Dataset Size on Classification Performance: An Empirical Evaluation in the Medical Domain", Appl. Sci., 11(2), (2021). CrossRef
- S. Walford, M. McB Page and S. P. Allison, "The Influence of Renal Threshold on the Interpretation of Urine Tests for Glucose in Diabetic Patients", Diabetes Care, 3(9), 672 (1980). CrossRef
- Thermo Fisher Scientific, "NanoDrop One Microvolume UV-Vis Spectrophotometers Product Specifications". DirectLink
- A.M.C. Davies and T. Fearn,"Back to basics: the principles of principal component analysis", Spectroscopy Europe/World, (2004). DirectLink
- N. Sancar and S. S. Tabrizi, "Machine learning approach for the detection of vitamin D level: a comparative study", BMC Medical Informatics and Decision Making, 23(219) (2023). CrossRef
- T. Pranckevičius, V. Marcinkevičius, "Comparison of Naïve Bayes, Random Forest, Decision Tree, Support Vector Machines, and Logistic Regression Classifiers for Text Reviews Classification", Baltic J. Modern Computing, 5(2), 221 (2017). CrossRef
- M. Marzejon, M. Kosowska, D. Majchrowicz, B. Buło-Piontecka, M. Wąsowicz and M. Jędrzejewska-Szczerska, "Label-free optical detection of cyclosporine in biological fluids", J. Biophoton., 12(4), e201800273 (2018). CrossRef
- S. Uddin, A. Khan, M. Hossain and M. Ali Moni, "Comparing different supervised machine learning algorithms for disease prediction", BMC Medical Informatics and Decision Making, 19, 281(2019). CrossRef
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